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| http://purl.uniprot.org/citations/27529982 | http://www.w3.org/2000/01/rdf-schema#comment | "Seeking human longevity association with gene polymorphisms in transcription factors in the Tatar ethnic group, we conducted an analysis for age-related genotype, frequencies in polymorphic sites of FOXO1A (rs4943794, 72327C>G) and FOXO3A (rs3800231, 35-2764A>G) genes. Genotyping was conducted by using the PCR-RFLP approach. According to the results of logistic regression analysis, during maturity and old age periods, a decrease in the number of FOXO1A*G/*G (OR = 0.984, P = 0.004) genotype carriers occurs and an increase in the number of FOXO1A*C/*G (OR = 1.035, P = 0.014) and FOXO1A*C/*C (OR = 1.024, P = 0.033) genotype carriers occurs in the sample of subjects before gender adjustments. In the sample of long-livers, the number of FOXO1A*C/*C (OR = 0.772, P = 0.028) genotype carriers decreased among women, while the number of FOXO3A*G/*G (OR = 1.008, P = 0.0001) genotype carriers increased among both men and women. Therefore, the FOXO1A gene polymorphic site rs4943794 is associated with an acquisition of old and senescent age in a sample before gender adjustments and with women's longevity. FOXO3A gene polymorphic site rs3800231 is associated with longevity in both women and men."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/author | "Mustafina O.E."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/author | "Nasibullin T.R."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/author | "Tuktarova I.A."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/author | "Erdman V.V."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/author | "Somova R.S.h."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/name | "Genetika"xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/pages | "474-481"xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/title | "[Analysis of FOXO1A and FOXO3A Gene Allele Association with Human Longevity]."xsd:string |
| http://purl.uniprot.org/citations/27529982 | http://purl.uniprot.org/core/volume | "52"xsd:string |
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