| http://purl.uniprot.org/citations/27543925 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27543925 | http://www.w3.org/2000/01/rdf-schema#comment | "The low sensitivity of C4d immunoreactivity in peritubular capillaries (PTCs) hinders its use in the diagnosis of chronic active antibody-mediated rejection (CAAMR). C4d-negative CAAMR was defined in the 2013 Banff classification, which included the expression of endothelial-associated transcripts (ENDATs). We previously showed that the ENDAT caveolin-1 (CAV-1) is a distinct feature of CAAMR. In this study, we investigated the prognostic value of CAV-1 immunoreactivity in PTCs in kidney transplant patients. Ninety-eight kidney transplant recipients were included in this study. The prognostic value of CAV-1 immunoreactivity in PTCs was evaluated by double immunostaining for CAV-1 and pathologische Anatomie Leiden endothelium (PAL-E, a PTC marker) in the PTCs of kidney allograft biopsy samples. The patients were divided into two groups: CAV-1/PAL-E<50% and CAV-1/PAL-E≥50%. Kaplan-Meier curves showed that CAV-1/PAL-E≥50% patients had a significantly worse prognosis than that of CAV-1/PAL-E<50% patients (log-rank; P<.001). C4d staining of PTCs was not associated with the development of graft failure (log-rank; P=.345), whereas in a multivariate Cox regression analysis, CAV-1 immunoreactivity in PTCs was independently associated with graft failure (hazard ratio: 11.1; P=.0324). CAV-1 immunoreactivity in PTCs may serve as a prognostic marker for kidney allograft survival."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.org/dc/terms/identifier | "doi:10.1111/ctr.12833"xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Ishida H."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Kobayashi A."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Nakada Y."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Yamamoto H."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Tanabe K."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Katsumata H."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Yamakawa T."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Yamamoto I."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Horita S."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Yokoo T."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Tanno Y."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Tsuboi N."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Ohkido I."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Kawabe M."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Okumi M."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Katsuma A."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/author | "Mafune A."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/name | "Clin Transplant"xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/pages | "1417-1424"xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/title | "The prognostic values of caveolin-1 immunoreactivity in peritubular capillaries in patients with kidney transplantation."xsd:string |
| http://purl.uniprot.org/citations/27543925 | http://purl.uniprot.org/core/volume | "30"xsd:string |