| http://purl.uniprot.org/citations/27548613 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27548613 | http://www.w3.org/2000/01/rdf-schema#comment | "The synaptonemal complex protein 1 (SYCP1) is the main structural element of transverse filaments (TFs) of the synaptonemal complex (SC), which is a meiosis-specific complex structure formed at the synapse of homologue chromosomes to hold them together. The N-terminal domain of SYCP1 is known to be located within the central elements (CEs), whereas the C-terminal domain is located toward lateral elements (LEs). SYCP1 is a well-known meiosis marker that is also known to be a prognostic marker in the early stage of several cancers including breast, gliomas, and ovarian cancers. The structure of SC, especially the TF structure formed mainly by SYCP1, remains unclear without any structural information. To elucidate a molecular basis of SC formation and function, we first solved the crystal structure of C-terminal coiled-coil domain of SYCP1. The coiled-coil domain of SYCP1 forms asymmetric, anti-parallel dimers in solution."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0161379"xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/author | "Choi J.Y."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/author | "Kim Y.G."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/author | "Park H.H."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/author | "Jeong J.H."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/author | "Seo E.K."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/pages | "e0161379"xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/title | "Crystal Structure of C-Terminal Coiled-Coil Domain of SYCP1 Reveals Non-Canonical Anti-Parallel Dimeric Structure of Transverse Filament at the Synaptonemal Complex."xsd:string |
| http://purl.uniprot.org/citations/27548613 | http://purl.uniprot.org/core/volume | "11"xsd:string |
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