http://purl.uniprot.org/citations/27567475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27567475 | http://www.w3.org/2000/01/rdf-schema#comment | "L-type amino acid transporter 1 (LAT1, SLC7A5) incorporates essential amino acids into cells. Recent studies have shown that LAT1 is a predominant transporter in various human cancers. However, the function of LAT1 in thymic carcinoma remains unknown. Here we demonstrate that LAT1 is a critical transporter for human thymic carcinoma cells. LAT1 was strongly expressed in human thymic carcinoma tissues. LAT1-specific inhibitor significantly suppressed leucine uptake and growth of Ty82 human thymic carcinoma cell lines, suggesting that thymic carcinoma takes advantage of LAT1 as a quality transporter and that LAT1-specific inhibitor might be clinically beneficial in therapy for thymic carcinoma."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jphs.2016.07.006"xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Hayashi K."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Maeda S."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Anzai N."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Endou H."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Ouchi M."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Jutabha P."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Chida M."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/author | "Supak Y."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/name | "J Pharmacol Sci"xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/pages | "201-204"xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/title | "LAT1 acts as a crucial transporter of amino acids in human thymic carcinoma cells."xsd:string |
http://purl.uniprot.org/citations/27567475 | http://purl.uniprot.org/core/volume | "132"xsd:string |
http://purl.uniprot.org/citations/27567475 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27567475 |
http://purl.uniprot.org/citations/27567475 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27567475 |
http://purl.uniprot.org/uniprot/#_A0A0C4DGL4-mappedCitation-27567475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27567475 |
http://purl.uniprot.org/uniprot/#_Q01650-mappedCitation-27567475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27567475 |
http://purl.uniprot.org/uniprot/#_Q2MCL6-mappedCitation-27567475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27567475 |
http://purl.uniprot.org/uniprot/#_Q96QB2-mappedCitation-27567475 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27567475 |
http://purl.uniprot.org/uniprot/Q01650 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27567475 |
http://purl.uniprot.org/uniprot/A0A0C4DGL4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27567475 |