http://purl.uniprot.org/citations/27623381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27623381 | http://www.w3.org/2000/01/rdf-schema#comment | "During M-phase entry in metazoans with open mitosis, the concerted action of mitotic kinases disassembles nuclei and promotes assembly of kinetochores-the primary microtubule attachment sites on chromosomes. At M-phase exit, these major changes in cellular architecture must be reversed. Here, we show that the conserved kinetochore-localized nucleoporin MEL-28/ELYS docks the catalytic subunit of protein phosphatase 1 (PP1c) to direct kinetochore disassembly-dependent chromosome segregation during oocyte meiosis I and nuclear assembly during the transition from M phase to interphase. During oocyte meiosis I, MEL-28-PP1c disassembles kinetochores in a timely manner to promote elongation of the acentrosomal spindles that segregate homologous chromosomes. During nuclear assembly, MEL-28 recruits PP1c to the periphery of decondensed chromatin, where it directs formation of a functional nuclear compartment. Thus, a pool of phosphatase activity associated with a kinetochore-localized nucleoporin contributes to two key events that occur during M-phase exit in metazoans: kinetochore disassembly and nuclear reassembly."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2016.08.006"xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Desai A."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Oegema K."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Lee K.Y."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Richardson A."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Dumont J."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Hattersley N."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Moyle M."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Cheerambathur D."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/author | "Stefanutti M."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/name | "Dev Cell"xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/pages | "463-477"xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/title | "A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly."xsd:string |
http://purl.uniprot.org/citations/27623381 | http://purl.uniprot.org/core/volume | "38"xsd:string |
http://purl.uniprot.org/citations/27623381 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27623381 |
http://purl.uniprot.org/citations/27623381 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27623381 |
http://purl.uniprot.org/uniprot/#_P34278-mappedCitation-27623381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27623381 |
http://purl.uniprot.org/uniprot/#_Q18508-mappedCitation-27623381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27623381 |
http://purl.uniprot.org/uniprot/#_P48727-mappedCitation-27623381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27623381 |
http://purl.uniprot.org/uniprot/#_Q27497-mappedCitation-27623381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27623381 |
http://purl.uniprot.org/uniprot/Q18508 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27623381 |
http://purl.uniprot.org/uniprot/P34278 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27623381 |