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http://purl.uniprot.org/citations/27624533http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27624533http://www.w3.org/2000/01/rdf-schema#comment"Fibroblast growth factor 23 (FGF23) is a potent regulator of phosphorus (P) and vitamin D metabolism. Long-term dietary magnesium (Mg) deficiency increases circulating levels of FGF23, whereas the effects of short-term dietary Mg deficiency are unclear. Thus, the present study investigated whether short-term dietary Mg deficiency affects circulating levels of FGF23. We also assessed changes in renal mRNA expression of vitamin D metabolizing enzymes and type II sodium-phosphate (Na/Pi) cotransporters, since these are regulated by FGF23. Rats were fed a control diet (control group) or an Mg-deficient diet (Mg-deficient group) for 2, 4 or 7 days. Serum Mg levels were significantly lower in the Mg-deficient group than in the control group at all time points. Serum FGF23 levels were significantly higher in the Mg-deficient group than in the control group at day 7. The 25-hydroxyvitamin D-24-hydroxylase (24(OH)ase) mRNA levels were significantly higher in the Mg-deficient group than in the control group at day 7 . No significant differences in types IIa and IIc Na/Pi cotransporter mRNA levels were observed between the control and Mg-deficient groups. These results suggest that dietary Mg deficiency causes a rapid increase in circulating levels of FGF23 and renal 24(OH)ase mRNA levels."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.org/dc/terms/identifier"doi:10.1684/mrh.2016.0401"xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/author"Maeda Y."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/author"Matsuzaki H."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/author"Kajita Y."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/author"Katsumata S."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/name"Magnes Res"xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/pages"48-54"xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/title"Changes in circulating levels of fibroblast growth factor 23 induced by short-term dietary magnesium deficiency in rats."xsd:string
http://purl.uniprot.org/citations/27624533http://purl.uniprot.org/core/volume"29"xsd:string
http://purl.uniprot.org/citations/27624533http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27624533
http://purl.uniprot.org/citations/27624533http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27624533
http://purl.uniprot.org/uniprot/#_A0A7U3JWB2-mappedCitation-27624533http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27624533
http://purl.uniprot.org/uniprot/#_A6ILX1-mappedCitation-27624533http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27624533
http://purl.uniprot.org/uniprot/#_Q8VI82-mappedCitation-27624533http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27624533
http://purl.uniprot.org/uniprot/A0A7U3JWB2http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/27624533
http://purl.uniprot.org/uniprot/A6ILX1http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/27624533
http://purl.uniprot.org/uniprot/Q8VI82http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/27624533