http://purl.uniprot.org/citations/27645581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27645581 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27645581 | http://www.w3.org/2000/01/rdf-schema#comment | "Lysyl oxidase-like 3 (LOXL3), a human disease gene candidate, is a member of the lysyl oxidase (LOX) family and is indispensable for mouse palatogenesis and vertebral column development. Our previous study showed that the loss of LOXL3 resulted in a severe cleft palate and spinal deformity. In this study, we investigated a possible role for LOXL3 in mouse embryonic lung development. LOXL3-deficient mice displayed reduced lung volumes and weights, diminished saccular spaces, and deformed and smaller thoracic cavities. Excess elastic fibres were detected in LOXL3-deficient lungs, which might be related to the increased LOXL4 expression. Increased transforming growth factor β1 (TGFβ1) expression might be involved in the up-regulation of LOXL4 in LOXL3-deficient lungs. We concluded that the loss of LOXL3 attenuates mouse embryonic lung development."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep33856"xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep33856"xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Gao J."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Gao J."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Li Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Li Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Lin Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Lin Z."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang T."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang T."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang A."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/author | "Zhang A."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/name | "Sci. Rep."xsd:string |
http://purl.uniprot.org/citations/27645581 | http://purl.uniprot.org/core/name | "Sci. Rep."xsd:string |