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http://purl.uniprot.org/citations/27650612http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27650612http://www.w3.org/2000/01/rdf-schema#comment"

Objective

It has been shown previously that the IL-23 receptor (IL-23R) variants are associated with ankylosing spondylitis (AS). It is unknown whether IL-23R is associated with AS in the Chinese population. The present study was performed to examine the association of IL-23R gene polymorphisms with susceptibility to AS in the Chinese population.

Methods

A total of 157 Chinese Han patients with AS and 150 ethnically matched healthy controls were enrolled. All patients were diagnosed with AS according to the modified New York criteria. 8 single nucleotide polymorphisms (SNPs) of the IL-23R gene cluster were genotyped.

Results

None of the 8 IL-23R SNPs were found to be associated with AS in the Chinese population.

Conclusion

The association of IL-23R and AS that is seen in Caucasian patients with AS is not present in Chinese patients with AS."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/author"Lin L."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/author"Wang S.L."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/author"Lu L.J."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/author"Su S.S."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/name"Ann Clin Lab Sci"xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/pages"470-473"xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/title"Association of Interleukin-23 Receptor Gene Single Nucleotide Polymorphisms with Ankylosing Spondylitis."xsd:string
http://purl.uniprot.org/citations/27650612http://purl.uniprot.org/core/volume"46"xsd:string
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