| http://purl.uniprot.org/citations/27655914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27655914 | http://www.w3.org/2000/01/rdf-schema#comment | "Protein tyrosine phosphatase MEG2 (PTP-MEG2) is a unique nonreceptor tyrosine phosphatase associated with transport vesicles, where it facilitates membrane trafficking by dephosphorylation of the N-ethylmaleimide-sensitive fusion factor. In this study, we identify the neurotrophin receptor TrkA as a novel cargo whose transport to the cell surface requires PTP-MEG2 activity. In addition, TrkA is also a novel substrate of PTP-MEG2, which dephosphorylates both Tyr-490 and Tyr-674/Tyr-675 of TrkA. As a result, overexpression of PTP-MEG2 down-regulates NGF/TrkA signaling and blocks neurite outgrowth and differentiation in PC12 cells and cortical neurons."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m116.728550"xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Zhang D."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Liang Z."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Ahmad M."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Zhao Z.J."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Sonntag W.E."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Ashpole N.M."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/author | "Marlin M.C."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/pages | "23895-23905"xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/title | "The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A."xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://purl.uniprot.org/core/volume | "291"xsd:string |
| http://purl.uniprot.org/citations/27655914 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27655914 |
| http://purl.uniprot.org/citations/27655914 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27655914 |
| http://purl.uniprot.org/uniprot/Q921M4#attribution-7B1133C2B0AB9780704934D58A98AB9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/P01139#attribution-7B1133C2B0AB9780704934D58A98AB9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/Q3UFB7#attribution-221A1217A84AE1AD4F21B3AD281EBD1A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/P04629#attribution-7B1133C2B0AB9780704934D58A98AB9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/P43378#attribution-7B1133C2B0AB9780704934D58A98AB9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/O35239#attribution-221A1217A84AE1AD4F21B3AD281EBD1A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |
| http://purl.uniprot.org/uniprot/O35239#attribution-7B1133C2B0AB9780704934D58A98AB9C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27655914 |