| http://purl.uniprot.org/citations/27684367 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27684367 | http://www.w3.org/2000/01/rdf-schema#comment | "Neuronal computation underlying detection of visual motion has been studied for more than a half-century. In Drosophila, direction-selective T4/T5 neurons show supralinear signal amplification in response to stimuli moving in their preferred direction, in agreement with the prediction made by the Hassenstein-Reichardt detector. Nevertheless, the molecular mechanism explaining how the Hassenstein-Reichardt model is implemented in T4/T5 cells has not been identified yet. In the present study, we utilized cell type-specific transcriptome profiling with RNA-seq to obtain a complete gene expression profile of T4/T5 neurons. We analyzed the expression of genes that affect neuronal computational properties and can underlie the molecular implementation of the core features of the Hassenstein-Reichardt model to the dendrites of T4/T5 neurons. Furthermore, we used the acquired RNA-seq data to examine the neurotransmitter system used by T4/T5 neurons. Surprisingly, we observed co-expression of the cholinergic markers and the vesicular GABA transporter in T4/T5 neurons. We verified the previously undetected expression of vesicular GABA transporter in T4/T5 cells using VGAT-LexA knock-in line. The provided gene expression dataset can serve as a useful source for studying the properties of direction-selective T4/T5 neurons on the molecular level."xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0163986"xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/author | "Pankova K."xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/author | "Borst A."xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/pages | "e0163986"xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/title | "RNA-Seq Transcriptome Analysis of Direction-Selective T4/T5 Neurons in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/27684367 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27684367 |
| http://purl.uniprot.org/citations/27684367 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27684367 |
| http://purl.uniprot.org/uniprot/#_A1Z9M6-mappedCitation-27684367 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27684367 |
| http://purl.uniprot.org/uniprot/#_P07668-mappedCitation-27684367 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27684367 |
| http://purl.uniprot.org/uniprot/P07668 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27684367 |
| http://purl.uniprot.org/uniprot/A1Z9M6 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27684367 |