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http://purl.uniprot.org/citations/27732795 | http://www.w3.org/2000/01/rdf-schema#comment | "Double-strand breaks (DSBs) pose a severe challenge to genome integrity; consequently, cells have developed efficient mechanisms to repair DSBs through several pathways of homologous recombination and other nonhomologous end-joining processes. Much of our understanding of these pathways has come from the analysis of site-specific DSBs created by the HO endonuclease in the budding yeast Saccharomyces cerevisiae. I was fortunate to get in on the ground floor of analyzing the fate of synchronously induced DSBs through the study of what I coined "in vivo biochemistry." I have had the remarkable good fortune to profit from the development of new techniques that have permitted an ever more detailed dissection of these repair mechanisms, which are described here."xsd:string |
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http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/author | "Haber J.E."xsd:string |
http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/name | "Annu Rev Genet"xsd:string |
http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/pages | "1-28"xsd:string |
http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/title | "A Life Investigating Pathways That Repair Broken Chromosomes."xsd:string |
http://purl.uniprot.org/citations/27732795 | http://purl.uniprot.org/core/volume | "50"xsd:string |
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