| http://purl.uniprot.org/citations/27733364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27733364 | http://www.w3.org/2000/01/rdf-schema#comment | "MicroRNAs play diverse roles in various physiological processes during Drosophila development. In the present study, we reported that miR-11 regulates pupal size during Drosophila metamorphosis via targeting Ras85D with the following evidences: pupal size was increased in the miR-11 deletion mutant; restoration of miR-11 in the miR-11 deletion mutant rescued the increased pupal size phenotype observed in the miR-11 deletion mutant; ectopic expression of miR-11 in brain insulin-producing cells (IPCs) and whole body shows consistent alteration of pupal size; Dilps and Ras85D expressions were negatively regulated by miR-11 in vivo; miR-11 targets Ras85D through directly binding to Ras85D 3'-untranslated region in vitro; removal of one copy of Ras85D in the miR-11 deletion mutant rescued the increased pupal size phenotype observed in the miR-11 deletion mutant. Thus, our current work provides a novel mechanism of pupal size determination by microRNAs during Drosophila melanogaster metamorphosis."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.org/dc/terms/identifier | "doi:10.1152/ajpcell.00190.2016"xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/author | "Chen L."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/author | "Li S."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/author | "Jin P."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/author | "Ma F."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/name | "Am J Physiol Cell Physiol"xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/pages | "C71-C82"xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/title | "miR-11 regulates pupal size of Drosophila melanogaster via directly targeting Ras85D."xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://purl.uniprot.org/core/volume | "312"xsd:string |
| http://purl.uniprot.org/citations/27733364 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27733364 |
| http://purl.uniprot.org/citations/27733364 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27733364 |
| http://purl.uniprot.org/uniprot/#_P08646-mappedCitation-27733364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27733364 |
| http://purl.uniprot.org/uniprot/#_P26675-mappedCitation-27733364 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27733364 |
| http://purl.uniprot.org/uniprot/P26675 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27733364 |
| http://purl.uniprot.org/uniprot/P08646 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/27733364 |