| http://purl.uniprot.org/citations/27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27739478 | http://www.w3.org/2000/01/rdf-schema#comment | "An induction of long-term cellular and humoral immunity is for the goal of vaccines, but the combination of antigens and adjuvant remain unclear. Here, we show, using a cellular vaccine carrying foreign protein antigen plus iNKT cell glycolipid antigen, designated as artificial adjuvant vector cells (aAVCs), that mature XCR1- DCs in situ elicit not only ordinal antigen-specific CD4+T cells, but also CD4+ Tfh and germinal center, resulted in inducing long-term antibody production. As a mechanism for leading the long-term antibody production by aAVC, memory CD4+ Tfh cells but not iNKTfh cells played an important role in a Bcl6 dependent manner. To develop it for influenza infection, we established influenza hemagglutinin-carrying aAVC (aAVC-HA) and found that all the mice vaccinated with aAVC-HA were protected from life-threatening influenza infection. Thus, the in vivo DC targeting therapy by aAVC would be useful for protection against viral infection."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep35173"xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Shimizu K."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Yamasaki S."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Sakurai M."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Kawamura M."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Fujii S.I."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/author | "Kometani K."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/pages | "35173"xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/title | "In vivo dendritic cell targeting cellular vaccine induces CD4+ Tfh cell-dependent antibody against influenza virus."xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/27739478 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27739478 |
| http://purl.uniprot.org/citations/27739478 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27739478 |
| http://purl.uniprot.org/uniprot/#_P70443-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J090-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_B9VQY2-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_E9Q395-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_P06332-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_P01731-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_O55054-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_P41183-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |
| http://purl.uniprot.org/uniprot/#_Q3UUV7-mappedCitation-27739478 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27739478 |