| http://purl.uniprot.org/citations/27756895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27756895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27756895 | http://www.w3.org/2000/01/rdf-schema#comment | "At neuronal synapses, multiprotein complexes of trans-synaptic adhesion molecules, scaffold proteins and neurotransmitter receptors assemble to essential building blocks required for synapse formation and maintenance. Here we describe a novel role for the membrane-associated guanylate kinase (MAGUK) protein MPP2 (MAGUK p55 subfamily member 2) at synapses of rat central neurons. Through interactions mediated by its C-terminal SH3-GK domain module, MPP2 binds to the abundant postsynaptic scaffold proteins PSD-95 and GKAP and localises to postsynaptic sites in hippocampal neurons. MPP2 also colocalises with the synaptic adhesion molecule SynCAM1. We demonstrate that the SynCAM1 C-terminus interacts directly with the MPP2 PDZ domain and that MPP2 does not interact in this manner with other highly abundant postsynaptic transmembrane proteins. Our results highlight a previously unexplored role for MPP2 at postsynaptic sites as a scaffold that links SynCAM1 cell adhesion molecules to core proteins of the postsynaptic density."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep35283"xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep35283"xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Wahl M.C."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Wahl M.C."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Lardong J.A."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Lardong J.A."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Rademacher N."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Rademacher N."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Schmerl B."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Schmerl B."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Shoichet S.A."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/author | "Shoichet S.A."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/name | "Sci. Rep."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/name | "Sci. Rep."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/pages | "35283"xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/pages | "35283"xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/title | "MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/title | "MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density."xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/27756895 | http://purl.uniprot.org/core/volume | "6"xsd:string |