| http://purl.uniprot.org/citations/27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/27775710 | http://www.w3.org/2000/01/rdf-schema#comment | "Nuclear export of preribosomal subunits is a key step during eukaryotic ribosome formation. To efficiently pass through the FG-repeat meshwork of the nuclear pore complex, the large pre-60S subunit requires several export factors. Here we describe the mechanism of recruitment of the Saccharomyces cerevisiae RNA-export receptor Mex67-Mtr2 to the pre-60S subunit at the proper time. Mex67-Mtr2 binds at the premature ribosomal-stalk region, which later during translation serves as a binding platform for translational GTPases on the mature ribosome. The assembly factor Mrt4, a structural homolog of cytoplasmic-stalk protein P0, masks this site, thus preventing untimely recruitment of Mex67-Mtr2 to nuclear pre-60S particles. Subsequently, Yvh1 triggers Mrt4 release in the nucleus, thereby creating a narrow time window for Mex67-Mtr2 association at this site and facilitating nuclear export of the large subunit. Thus, a spatiotemporal mark on the ribosomal stalk controls the recruitment of an RNA-export receptor to the nascent 60S subunit."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb.3312"xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/author | "Sarkar A."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/author | "Pech M."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/author | "Hurt E."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/author | "Beckmann R."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/author | "Thoms M."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/name | "Nat Struct Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/pages | "1074-1082"xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/title | "Ribosome-stalk biogenesis is coupled with recruitment of nuclear-export factor to the nascent 60S subunit."xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://purl.uniprot.org/core/volume | "23"xsd:string |
| http://purl.uniprot.org/citations/27775710 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27775710 |
| http://purl.uniprot.org/citations/27775710 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27775710 |
| http://purl.uniprot.org/uniprot/#_A0A8H4F9N8-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_A0A6A5PVH9-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_P34232-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_P05317-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_P0CX53-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_P0CX54-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_Q03862-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_Q02256-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_P33201-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |
| http://purl.uniprot.org/uniprot/#_Q12522-mappedCitation-27775710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27775710 |