| http://purl.uniprot.org/citations/2777802 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2777802 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2777802 | http://www.w3.org/2000/01/rdf-schema#comment | "Carp parvalbumin coordinates calcium through one carbonyl oxygen atom and the oxygen-containing side chains of 5 amino acid residues, or 4 residues and a water molecule, in a helix-loop-helix structural motif. Other calcium-binding proteins, including calmodulin and troponin C, also possess this unique calcium-binding design, which is designated EF-hand or calmodulin fold. Parvalbumin has two such sites, labeled CD and EF. Each of the calcium-binding sites of refined structures of proteins belonging to this group has a 7-oxygen coordination sphere except those of the structure of parvalbumin as it was reported in 1975. This structure had been refined at 1.9 A using difference Fourier techniques on film data. The CD site appeared to be 6-coordinate and the EF site 8-coordinate. Results of NMR experiments using 113Cd-substituted parvalbumin, however, indicate that the sites are similar to one another with coordination number greater than 6. To resolve the inconsistency between crystallographic and NMR results, 1.6 A area detector data was collected for native and cadmium-substituted parvalbumin; the structures have been refined to R factors of 18.7% and 16.4%, respectively, with acceptable geometry and low errors in atomic coordinates. Differences between the parvalbumin structure described in 1975 and the present structure are addressed, including the discovery of 7-coordination for both the CD and EF sites."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)84751-8"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)84751-8"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Swain A.L."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Swain A.L."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Kretsinger R.H."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Kretsinger R.H."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Amma E.L."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/author | "Amma E.L."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/pages | "16620-16628"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/pages | "16620-16628"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/title | "Restrained least squares refinement of native (calcium) and cadmium-substituted carp parvalbumin using X-ray crystallographic data at 1.6-A resolution."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/title | "Restrained least squares refinement of native (calcium) and cadmium-substituted carp parvalbumin using X-ray crystallographic data at 1.6-A resolution."xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/volume | "264"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://purl.uniprot.org/core/volume | "264"xsd:string |
| http://purl.uniprot.org/citations/2777802 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2777802 |
| http://purl.uniprot.org/citations/2777802 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2777802 |
| http://purl.uniprot.org/citations/2777802 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2777802 |
| http://purl.uniprot.org/citations/2777802 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2777802 |