| http://purl.uniprot.org/citations/2777807 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2777807 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2777807 | http://www.w3.org/2000/01/rdf-schema#comment | "Feedback repression of the genes encoding the low density lipoprotein receptor and several enzymes of the cholesterol biosynthetic pathway is mediated by 25-hydroxycholesterol and other oxysterols. In this study, we have cloned a rabbit cDNA encoding an oxysterol-binding protein that may play a role in this regulation. The predicted amino acid sequence revealed a protein of 809 amino acids with two distinctive features: 1) a glycine- and alanine-rich region (63% of 80 residues) at the NH2 terminus, and 2) a 35-residue leucine zipper motif that may mediate the previously observed oligomerization of the protein. When transfected into simian COS cells, the rabbit cDNA produced a protein that exhibited the same affinity and specificity for sterols as the previously purified hamster liver protein. Immunoblotting analysis showed that the rabbit cDNA encodes both the 96- and 101-kilodalton forms of the oxysterol-binding protein that were previously observed. The availability of an expressible cDNA for the oxysterol-binding protein should help elucidate its role in sterol metabolism."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)84776-2"xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(19)84776-2"xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Slaughter C.A."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Slaughter C.A."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Brown M.S."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Brown M.S."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Goldstein J.L."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Goldstein J.L."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Dawson P.A."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Dawson P.A."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Ridgway N.D."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/author | "Ridgway N.D."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/date | "1989"xsd:gYear |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/pages | "16798-16803"xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/pages | "16798-16803"xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/title | "cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/title | "cDNA cloning and expression of oxysterol-binding protein, an oligomer with a potential leucine zipper."xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/volume | "264"xsd:string |
| http://purl.uniprot.org/citations/2777807 | http://purl.uniprot.org/core/volume | "264"xsd:string |