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http://purl.uniprot.org/citations/2792078http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2792078http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2792078http://www.w3.org/2000/01/rdf-schema#comment"We demonstrate here that the human oestrogen receptor (hER) cDNA clone pOR8 obtained from MCF-7 cells contains an artefactual point mutation which results in the substitution of a valine for a glycine at amino acid position 400 (Gly-400----Val-400). This mutation in the hormone binding domain of the cloned hER destabilizes its structure and decreases its apparent affinity for oestradiol at 25 degrees C, but not at 4 degrees C, when compared with the wild-type hER with a Gly-400."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1989.tb03604.x"xsd:string
http://purl.uniprot.org/citations/2792078http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1989.tb03604.x"xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Park I."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Park I."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Mullick A."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Mullick A."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Chambon P."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Chambon P."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Metzger D."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Metzger D."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Tora L."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Tora L."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Ponglikitmongkol M."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/author"Ponglikitmongkol M."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/date"1989"xsd:gYear
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/pages"1981-1986"xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/pages"1981-1986"xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/title"The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties."xsd:string
http://purl.uniprot.org/citations/2792078http://purl.uniprot.org/core/title"The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties."xsd:string