http://purl.uniprot.org/citations/27921409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27921409 | http://www.w3.org/2000/01/rdf-schema#comment | "Recurrent aphthous stomatitis (RAS) is known as the most common chronic disease of the oral cavity, which affects a range of 5-25% of the population. RAS appears to be associated with some human leukocyte antigen (HLA) class II alleles and haplotypes. This study attempts to survey the distribution of HLA-DRB and -DQB alleles among Iranian RAS patients and healthy controls. In order to evaluate the association of HLA-DR and DQ alleles and haplotypes, 54 patients with RAS and 100 unrelated healthy subjects as control group were investigated. Our data indicated that DRB1*13:17, DRB1*15:01, and DRB5*01 were significantly more frequent in RAS patients in comparison to controls. However, DRB3:01allele frequency was higher in the controls compared to the patients. The significantly frequent allele in the patients compared with the healthy subjects was HLA-DQB1*03:02. However, both HLA-DQB1*02:01 and HLA-DQB1*03:01 alleles were most frequent in the healthy individuals rather than the patients. The DRB*04/DQB1*03:01 and DRB*01:01/DQB1*02:01 haplotypes were significantly distributed in healthy subjects compared with patients. However, DRB*07:01/DQB1*03:02 haplotype was found to be significantly frequent in patients than controls. In respect of HLA genes, factors are involved in the incidence of RAS; various HLA-DRB and HLA-DQB1 alleles and the related haplotypes are suggested to be the three main RAS susceptibility factors in our population study."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Rezaei N."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Mahmoudi M."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Mohammadzadeh M."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Aslani S."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Najafi S."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Meighani G."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/author | "Zare Bidoki A."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/date | "2016"xsd:gYear |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/name | "Iran J Allergy Asthma Immunol"xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/pages | "289-295"xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/title | "HLA-DRB and HLA-DQB Allele and Haplotype Frequencies in Iranian Patients with Recurrent Aphthous Stomatitis."xsd:string |
http://purl.uniprot.org/citations/27921409 | http://purl.uniprot.org/core/volume | "15"xsd:string |
http://purl.uniprot.org/citations/27921409 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27921409 |
http://purl.uniprot.org/citations/27921409 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27921409 |
http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-27921409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27921409 |
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http://purl.uniprot.org/uniprot/#_A0A0A7C853-mappedCitation-27921409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27921409 |
http://purl.uniprot.org/uniprot/#_A0A0A7CAC7-mappedCitation-27921409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27921409 |
http://purl.uniprot.org/uniprot/#_A0A0A7CAE0-mappedCitation-27921409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/27921409 |
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