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http://purl.uniprot.org/citations/27980088http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27980088http://www.w3.org/2000/01/rdf-schema#comment"The small subunit (SSU) processome, a large ribonucleoprotein particle, organizes the assembly of the eukaryotic small ribosomal subunit by coordinating the folding, cleavage, and modification of nascent pre-ribosomal RNA (rRNA). Here, we present the cryo-electron microscopy structure of the yeast SSU processome at 5.1-angstrom resolution. The structure reveals how large ribosome biogenesis complexes assist the 5' external transcribed spacer and U3 small nucleolar RNA in providing an intertwined RNA-protein assembly platform for the separate maturation of 18S rRNA domains. The strategic placement of a molecular motor at the center of the particle further suggests a mechanism for mediating conformational changes within this giant particle. This study provides a structural framework for a mechanistic understanding of eukaryotic ribosome assembly in the model organism Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.org/dc/terms/identifier"doi:10.1126/science.aal1880"xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/author"Klinge S."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/author"Chaker-Margot M."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/author"Barandun J."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/author"Hunziker M."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/pages"eaal1880"xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/title"Architecture of the yeast small subunit processome."xsd:string
http://purl.uniprot.org/citations/27980088http://purl.uniprot.org/core/volume"355"xsd:string
http://purl.uniprot.org/citations/27980088http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27980088
http://purl.uniprot.org/citations/27980088http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27980088
http://purl.uniprot.org/uniprot/Q12247#attribution-A7FE486A2871F2C686BF2A93304E0710http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/Q12247#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/Q08965#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P39985#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P38333#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/Q12099#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P43639#attribution-A7FE486A2871F2C686BF2A93304E0710http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P43639#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P15790#attribution-A7FE486A2871F2C686BF2A93304E0710http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P15790#attribution-B6A9A16B2051B0FB8942C17B362D1563http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088
http://purl.uniprot.org/uniprot/P19454#attribution-A7FE486A2871F2C686BF2A93304E0710http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/27980088