http://purl.uniprot.org/citations/27980088 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/27980088 | http://www.w3.org/2000/01/rdf-schema#comment | "The small subunit (SSU) processome, a large ribonucleoprotein particle, organizes the assembly of the eukaryotic small ribosomal subunit by coordinating the folding, cleavage, and modification of nascent pre-ribosomal RNA (rRNA). Here, we present the cryo-electron microscopy structure of the yeast SSU processome at 5.1-angstrom resolution. The structure reveals how large ribosome biogenesis complexes assist the 5' external transcribed spacer and U3 small nucleolar RNA in providing an intertwined RNA-protein assembly platform for the separate maturation of 18S rRNA domains. The strategic placement of a molecular motor at the center of the particle further suggests a mechanism for mediating conformational changes within this giant particle. This study provides a structural framework for a mechanistic understanding of eukaryotic ribosome assembly in the model organism Saccharomyces cerevisiae."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.aal1880"xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/author | "Klinge S."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/author | "Chaker-Margot M."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/author | "Barandun J."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/author | "Hunziker M."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/pages | "eaal1880"xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/title | "Architecture of the yeast small subunit processome."xsd:string |
http://purl.uniprot.org/citations/27980088 | http://purl.uniprot.org/core/volume | "355"xsd:string |
http://purl.uniprot.org/citations/27980088 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/27980088 |
http://purl.uniprot.org/citations/27980088 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/27980088 |
http://purl.uniprot.org/uniprot/Q12247#attribution-A7FE486A2871F2C686BF2A93304E0710 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/Q12247#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/Q08965#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P39985#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P38333#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/Q12099#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P43639#attribution-A7FE486A2871F2C686BF2A93304E0710 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P43639#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P15790#attribution-A7FE486A2871F2C686BF2A93304E0710 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P15790#attribution-B6A9A16B2051B0FB8942C17B362D1563 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |
http://purl.uniprot.org/uniprot/P19454#attribution-A7FE486A2871F2C686BF2A93304E0710 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/27980088 |