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http://purl.uniprot.org/citations/27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/27984744http://www.w3.org/2000/01/rdf-schema#comment"Quiescence (G0) is a ubiquitous stress response through which cells enter reversible dormancy, acquiring distinct properties including reduced metabolism, resistance to stress, and long life. G0 entry involves dramatic changes to chromatin and transcription of cells, but the mechanisms coordinating these processes remain poorly understood. Using the fission yeast, here, we track G0-associated chromatin and transcriptional changes temporally and show that as cells enter G0, their survival and global gene expression programs become increasingly dependent on Clr4/SUV39H, the sole histone H3 lysine 9 (H3K9) methyltransferase, and RNAi proteins. Notably, G0 entry results in RNAi-dependent H3K9 methylation of several euchromatic pockets, prior to which Argonaute1-associated small RNAs from these regions emerge. Overall, our data reveal another function for constitutive heterochromatin proteins (the establishment of the global G0 transcriptional program) and suggest that stress-induced alterations in Argonaute-associated sRNAs can target the deployment of transcriptional regulatory proteins to specific sequences."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.org/dc/terms/identifier"doi:10.1016/j.molcel.2016.11.020"xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Aryee M.J."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Calvo I.A."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Sadreyev R.I."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Mistry M."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Khanduja J.S."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Motamedi M."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Ho Sui S.J."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Savol A.J."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Joh R.I."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/author"Palmieri C.M."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/date"2016"xsd:gYear
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/name"Mol Cell"xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/pages"1088-1101"xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/title"Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs."xsd:string
http://purl.uniprot.org/citations/27984744http://purl.uniprot.org/core/volume"64"xsd:string
http://purl.uniprot.org/citations/27984744http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/27984744
http://purl.uniprot.org/citations/27984744http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/27984744
http://purl.uniprot.org/uniprot/#_O42934-mappedCitation-27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27984744
http://purl.uniprot.org/uniprot/#_P09988-mappedCitation-27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27984744
http://purl.uniprot.org/uniprot/#_O60016-mappedCitation-27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27984744
http://purl.uniprot.org/uniprot/#_O14227-mappedCitation-27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27984744
http://purl.uniprot.org/uniprot/#_O74957-mappedCitation-27984744http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/27984744