| http://purl.uniprot.org/citations/28009483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28009483 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcription factors CBF1/2/3 are reported to play a dominant role in the cold responsive network of Arabidopsis by directly regulating the expression levels of cold responsive (COR) genes. In this study, we obtained CRISPR/Cas9-mediated loss-of-function mutants of cbf1∼3. Over 3,000 COR genes identified by RNA-seq analysis showed a slight but significant change in their expression levels in the mutants compared to the wild-type plants after being treated at 4 °C for 12 h. The C-repeat (CRT) motif (5'-CCGAC-3') was enriched in promoters of genes that were up-regulated by CBF2 and CBF3 but not in promoters of genes up-regulated by CBF1. These data suggest that CBF2 and CBF3 play a more important role in directing the cold response by regulating different sets of downstream COR genes. More than 2/3 of COR genes were co-regulated by two or three CBFs and were involved mainly in cellular signal transduction and metabolic processes; less than 1/3 of the genes were regulated by one CBF, and those genes up-regulated were enriched in cold-related abiotic stress responses. Our results indicate that CBFs play an important role in the trade-off between cold tolerance and plant growth through the precise regulation of COR genes in the complicated transcriptional network."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.org/dc/terms/identifier | "doi:10.1111/jipb.12515"xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Huang J."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Gu H."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Sun T."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Wang X."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Zhu C."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/author | "Ai Y."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/name | "J Integr Plant Biol"xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/pages | "118-133"xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/title | "The precise regulation of different COR genes by individual CBF transcription factors in Arabidopsis thaliana."xsd:string |
| http://purl.uniprot.org/citations/28009483 | http://purl.uniprot.org/core/volume | "59"xsd:string |
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