| http://purl.uniprot.org/citations/28024184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28024184 | http://www.w3.org/2000/01/rdf-schema#comment | "Serpinb9 (Sb9, also called Spi6) is an intracellular inhibitor of granzyme B (grB) that protects cytotoxic lymphocytes from grB-mediated death. In addition, Sb9 is also expressed in accessory immune cells, including dendritic cells (DCs), although its role is debated. Recently, we have demonstrated that Sb9 plays a grB-independent role in cross-presentation of antigens by CD8+ DCs. Here, using a mouse line expressing green fluorescent protein knocked in under the control of the Sb9 promoter, we demonstrate that Sb9 expression is highest in those tissue-resident and migratory DC subsets capable of cross-presentation. Further, we show that CD8+ DCs can be divided into two subsets based on Sb9 expression, and that only the subset expressing higher levels of Sb9 is capable of cross-presentation. These findings add support for role for Sb9 cross-presentation, and indicate that high Sb9 expression is a novel marker of cross-presentation capable DCs."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molimm.2016.12.011"xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Mitchell A.J."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Bird P.I."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Villadangos J.A."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Kaiserman D."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Roediger B."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Mangan M.S."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Rizzitelli A."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Vega-Ramos J."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Joeckel L.T."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/author | "Weninger W.W."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/name | "Mol Immunol"xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/pages | "50-56"xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/title | "Serpinb9 is a marker of antigen cross-presenting dendritic cells."xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://purl.uniprot.org/core/volume | "82"xsd:string |
| http://purl.uniprot.org/citations/28024184 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28024184 |
| http://purl.uniprot.org/citations/28024184 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28024184 |
| http://purl.uniprot.org/uniprot/#_O08797-mappedCitation-28024184 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28024184 |
| http://purl.uniprot.org/uniprot/O08797 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/28024184 |