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http://purl.uniprot.org/citations/28041852http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28041852http://www.w3.org/2000/01/rdf-schema#comment"The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR-recipient zone (LTMR-RZ), a role for LTMR-RZ processing in tactile perception, and the basic logic of LTMR-RZ organization. We found an unexpectedly high degree of neuronal diversity in the LTMR-RZ: seven excitatory and four inhibitory subtypes of interneurons exhibiting unique morphological, physiological, and synaptic properties. Remarkably, LTMRs form synapses on between four and 11 LTMR-RZ interneuron subtypes, while each LTMR-RZ interneuron subtype samples inputs from at least one to three LTMR classes, as well as spinal cord interneurons and corticospinal neurons. Thus, the LTMR-RZ is a somatosensory processing region endowed with a neuronal complexity that rivals the retina and functions to pattern the activity of ascending touch pathways that underlie tactile perception."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2016.12.010"xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Watanabe M."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Boyle K.A."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Bai L."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Heintz N."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Zhuo J."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Ginty D.D."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Dymecki S.M."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Song B.J."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Abraira V.E."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Nelson S.B."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Niederkofler V."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Springel M.W."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Zimmerman A.L."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Rutlin M."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Hughes D.I."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Kus L."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Orefice L.L."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Chirila A.M."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Kuehn E.D."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Bashista K.A."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"Hoynoski J."xsd:string
http://purl.uniprot.org/citations/28041852http://purl.uniprot.org/core/author"O'Neill T.G."xsd:string