| http://purl.uniprot.org/citations/28043918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28043918 | http://www.w3.org/2000/01/rdf-schema#comment | "Glutathione S-transferases (GSTs) enzymes are involved in the detoxification of several endogenous and exogenous substances. In this study, we evaluated the effects of two glutathione S-transferase polymorphisms, (GSTM1 and GSTT1) on bipolar disorder (BPD) risk susceptibility in a Tunisian population. These polymorphisms were analyzed in 229 healthy subjects and 109 patients with BPD, using a polymerase chain reaction. Statistical analysis was performed using SPSS 18.0. The relative associations between the GSTs genotypes and BPD were assessed by calculating odds ratios (ORs) and 95% confidence intervals (CLs). The study results demonstrated that individuals with GSTM1 [OR=1.51, 95% CI: 0.93-2.45, p=0.081] or GSTT1 [OR=1.65, 95% CI: 0.95-2.88, p=0.060] were not associated with the risk of BPD, whereas a significant association was found between individuals with both GSTM1/T1 null genotype and BPD risk [OR=2.96, 95% CI (1.26-7.03), p=0.005]. These genotyping finding revealed that the absence of both GSTM1 and GSTT1 activity could be a contributor factor for the development of BPD."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.gene.2016.12.035"xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Elouaer A."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Jrad B.B."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Saguem S."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Gaha L."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Nouira M."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Chbili C."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/author | "Fathallah N."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/pages | "31-35"xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/title | "Effects of glutathione S-transferase M1 andT1 deletions on bipolar disorder risk among a Tunisian population."xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://purl.uniprot.org/core/volume | "607"xsd:string |
| http://purl.uniprot.org/citations/28043918 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28043918 |
| http://purl.uniprot.org/citations/28043918 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28043918 |
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| http://purl.uniprot.org/uniprot/#_A0A0G2JRN4-mappedCitation-28043918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28043918 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JRQ5-mappedCitation-28043918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28043918 |
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| http://purl.uniprot.org/uniprot/#_Q16041-mappedCitation-28043918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28043918 |