| http://purl.uniprot.org/citations/28087693 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28087693 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28087693 | http://www.w3.org/2000/01/rdf-schema#comment | "The Canadian beaver (Castor canadensis) is the largest indigenous rodent in North America. We report a draft annotated assembly of the beaver genome, the first for a large rodent and the first mammalian genome assembled directly from uncorrected and moderate coverage (< 30 ×) long reads generated by single-molecule sequencing. The genome size is 2.7 Gb estimated by k-mer analysis. We assembled the beaver genome using the new Canu assembler optimized for noisy reads. The resulting assembly was refined using Pilon supported by short reads (80 ×) and checked for accuracy by congruency against an independent short read assembly. We scaffolded the assembly using the exon-gene models derived from 9805 full-length open reading frames (FL-ORFs) constructed from the beaver leukocyte and muscle transcriptomes. The final assembly comprised 22,515 contigs with an N50 of 278,680 bp and an N50-scaffold of 317,558 bp. Maximum contig and scaffold lengths were 3.3 and 4.2 Mb, respectively, with a combined scaffold length representing 92% of the estimated genome size. The completeness and accuracy of the scaffold assembly was demonstrated by the precise exon placement for 91.1% of the 9805 assembled FL-ORFs and 83.1% of the BUSCO (Benchmarking Universal Single-Copy Orthologs) gene set used to assess the quality of genome assemblies. Well-represented were genes involved in dentition and enamel deposition, defining characteristics of rodents with which the beaver is well-endowed. The study provides insights for genome assembly and an important genomics resource for Castoridae and rodent evolutionary biology."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.org/dc/terms/identifier | "doi:10.1534/g3.116.038208"xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.org/dc/terms/identifier | "doi:10.1534/g3.116.038208"xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Chen N."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Chen N."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Hu Z."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Hu Z."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Lok S."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Lok S."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Singh N."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Singh N."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Wang Z."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Wang Z."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Wang T."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Walker S."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Walker S."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Scherer S.W."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Scherer S.W."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Ng K."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Ng K."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Pereira S.L."xsd:string |
| http://purl.uniprot.org/citations/28087693 | http://purl.uniprot.org/core/author | "Pereira S.L."xsd:string |