http://purl.uniprot.org/citations/28107768 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28107768 | http://www.w3.org/2000/01/rdf-schema#comment | "Polar growth of root hairs is critical for plant survival and requires fine-tuned Rho of plants (ROP) signaling. Multiple ROP regulators participate in root hair growth. However, protein S-acyl transferases (PATs), mediating the S-acylation and membrane partitioning of ROPs, are yet to be found. Using a reverse genetic approach, combining fluorescence probes, pharmacological drugs, site-directed mutagenesis and genetic analysis with related root-hair mutants, we have identified and characterized an Arabidopsis PAT, which may be responsible for ROP2 S-acylation in root hairs. Specifically, functional loss of PAT4 resulted in reduced root hair elongation, which was rescued by a wild-type but not an enzyme-inactive PAT4. Membrane-associated ROP2 was significantly reduced in pat4, similar to S-acylation-deficient ROP2 in the wild type. We further showed that PAT4 and SCN1, a ROP regulator, additively mediate the stability and targeting of ROP2. The results presented here indicate that PAT4-mediated S-acylation mediates the membrane association of ROP2 at the root hair apex and provide novel insights into dynamic ROP signaling during plant tip growth."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.org/dc/terms/identifier | "doi:10.1111/tpj.13484"xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Chai S."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Li S."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Feng Q.N."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Ge F.R."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/author | "Wan Z.Y."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/name | "Plant J"xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/pages | "249-260"xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/title | "Arabidopsis PROTEIN S-ACYL TRANSFERASE4 mediates root hair growth."xsd:string |
http://purl.uniprot.org/citations/28107768 | http://purl.uniprot.org/core/volume | "90"xsd:string |
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