| http://purl.uniprot.org/citations/28230289 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28230289 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28230289 | http://www.w3.org/2000/01/rdf-schema#comment | "The abnormal expression and function of myelin-related proteins contribute to nervous system dysfunction associated with neuropsychiatric disorders; however, the underlying mechanism of this remains unclear. We found here that breast carcinoma amplified sequence 1 (BCAS1), a basic protein abundant in the brain, was expressed specifically in oligodendrocytes and Schwann cells, and that its expression level was decreased by demyelination. This suggests that BCAS1 is a novel myelin-associated protein. BCAS1 knockout mice displayed schizophrenia-like behavioral abnormalities and a tendency toward reduced anxiety-like behaviors. Moreover, we found that the loss of BCAS1 specifically induced hypomyelination and the expression of inflammation-related genes in the brain. These observations provide a novel insight into the functional link between oligodendrocytes and inflammation and/or abnormal behaviors."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.org/dc/terms/identifier | "doi:10.1002/glia.23129"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.org/dc/terms/identifier | "doi:10.1002/glia.23129"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Inoue R."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Inoue R."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Mori H."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Mori H."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Koike M."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Koike M."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Ninomiya K."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Ninomiya K."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Ishimoto T."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Ishimoto T."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Uchiyama Y."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/author | "Uchiyama Y."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/name | "Glia"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/name | "Glia"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/pages | "727-739"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/pages | "727-739"xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/title | "Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain."xsd:string |
| http://purl.uniprot.org/citations/28230289 | http://purl.uniprot.org/core/title | "Mice lacking BCAS1, a novel myelin-associated protein, display hypomyelination, schizophrenia-like abnormal behaviors, and upregulation of inflammatory genes in the brain."xsd:string |