| http://purl.uniprot.org/citations/28244369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28244369 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28244369 | http://www.w3.org/2000/01/rdf-schema#comment | "Sleep is a behavior that is found in all animals that have a nervous system and that have been studied carefully. In Caenorhabditis elegans larvae, sleep is associated with a turning behavior, called flipping, in which animals rotate 180° about their longitudinal axis. However, the molecular and neural substrates of this enigmatic behavior are not known. Here, we identified the conserved NK-2 homeobox gene ceh-24 to be crucially required for flipping. ceh-24 is required for the formation of processes and for cholinergic function of sublateral motor neurons, which separately innervate the four body muscle quadrants. Knockdown of cholinergic function in a subset of these sublateral neurons, the SIAs, abolishes flipping. The SIAs depolarize during flipping and their optogenetic activation induces flipping in a fraction of events. Thus, we identified the sublateral SIA neurons to control the three-dimensional movements of flipping. These neurons may also control other types of motion."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.24846"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.org/dc/terms/identifier | "doi:10.7554/elife.24846"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/author | "Schwarz J."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/author | "Schwarz J."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/author | "Bringmann H."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/author | "Bringmann H."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/name | "Elife"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/title | "Analysis of the NK2 homeobox gene ceh-24 reveals sublateral motor neuron control of left-right turning during sleep."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/title | "Analysis of the NK2 homeobox gene ceh-24 reveals sublateral motor neuron control of left-right turning during sleep."xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://purl.uniprot.org/core/volume | "6"xsd:string |
| http://purl.uniprot.org/citations/28244369 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28244369 |
| http://purl.uniprot.org/citations/28244369 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28244369 |
| http://purl.uniprot.org/citations/28244369 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28244369 |
| http://purl.uniprot.org/citations/28244369 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28244369 |
| http://purl.uniprot.org/uniprot/P34711 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/28244369 |
| http://purl.uniprot.org/uniprot/Q9NLC2 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/28244369 |
| http://purl.uniprot.org/uniprot/P32756 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/28244369 |
| http://purl.uniprot.org/uniprot/P32756#attribution-E69EDBEF215DCC0173283C8F3C5E9B95 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/28244369 |