http://purl.uniprot.org/citations/28251884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28251884 | http://www.w3.org/2000/01/rdf-schema#comment | "miR-101-3p has been identified as a tumor suppressor in several cancers, but its exact role in gastric adenocarcinoma is still largely unknown. In this study, we found that, compared with the RGM-1 human normal gastric epithelial cells, miR-101-3p was significantly downregulated in all six human gastric adenocarcinoma cell lines, including BGC-823, MNK-45, MGC-803, SGC-7901, AGS, and HGC-27. Overexpression of miR-101-3p suppressed both the proliferation and invasion of AGS gastric adenocarcinoma cells, and knockdown of miR-101-3p displayed the opposite effect. In addition, miR-101-3p could directly target and suppress the expression of the serum response factor (SRF) gene, which is a transcription factor of HOTAIR, a well-characterized tumor promoter lncRNA. miR-101-3p negatively regulated SRF-mediated transcription of HOTAIR. Moreover, silencing of either SRF or HOTAIR could counteract the promotion of gastric adenocarcinoma cell proliferation and invasion by miR-101-3p inhibition. Our findings indicate that miR-101-3p suppresses HOTAIR-induced proliferation and invasion through directly targeting SRF in gastric carcinoma cells."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.org/dc/terms/identifier | "doi:10.3727/096504017x14879366402279"xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Chen C."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Liu J."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Liu F."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Wu G."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Zhou J."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Wu Z."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Wu X."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/author | "Zhai J."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/name | "Oncol Res"xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/pages | "1383-1390"xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/title | "miR-101-3p Suppresses HOX Transcript Antisense RNA (HOTAIR)-Induced Proliferation and Invasion Through Directly Targeting SRF in Gastric Carcinoma Cells."xsd:string |
http://purl.uniprot.org/citations/28251884 | http://purl.uniprot.org/core/volume | "25"xsd:string |
http://purl.uniprot.org/citations/28251884 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28251884 |
http://purl.uniprot.org/citations/28251884 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28251884 |
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http://purl.uniprot.org/uniprot/#_P11831-mappedCitation-28251884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28251884 |
http://purl.uniprot.org/uniprot/#_Q59GI1-mappedCitation-28251884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28251884 |
http://purl.uniprot.org/uniprot/B4DU24 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/28251884 |
http://purl.uniprot.org/uniprot/P11831 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/28251884 |
http://purl.uniprot.org/uniprot/Q59GI1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/28251884 |