http://purl.uniprot.org/citations/28259580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28259580 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28259580 | http://www.w3.org/2000/01/rdf-schema#comment | "As an emerging contaminant, 1-H-benzotriazole (1H-BTR) has been detected in the engineered and natural aquatic environments, which usually coexists with heavy metals and causes combined pollution. In the present study, wild-type and transgenic zebrafish Danio rerio were used to explore the acute toxicity as well as the single and joint hepatotoxicity of cadmium (Cd) and 1H-BTR. Although the acute toxicity of 1H-BTR to zebrafish was low, increased expression of liver-specific fatty acid binding protein was observed in transgenic zebrafish when the embryos were exposed to 5.0 μM of 1H-BTR for 30 days. Besides, co-exposure to 1H-BTR not only reduced the acute toxic effects induced by Cd, but also alleviated the Cd-induced liver atrophy in transgenic fish. Correspondingly, effects of combined exposure to 1H-BTR on the Cd-induced expressions of several signal pathway-related genes and superoxide dismutase and glutathione-s-transferase proteins were studied. Based on the determination of Cd bioaccumulation in fish and the complexing stability constant (β) of Cd-BTR complex in solution, the detoxification mechanism of co-existing 1H-BTR on Cd to the zebrafish was discussed."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.envpol.2017.02.055"xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Feng Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Feng Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Gong Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Gong Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Li C."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Li C."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Sun H."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Sun H."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Zhang H."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Wang L."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Xing Y."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Xing Y."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Duan Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/author | "Duan Z."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/name | "Environ. Pollut."xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/name | "Environ Pollut"xsd:string |
http://purl.uniprot.org/citations/28259580 | http://purl.uniprot.org/core/pages | "706-713"xsd:string |