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http://purl.uniprot.org/citations/28288917http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28288917http://www.w3.org/2000/01/rdf-schema#comment"Cyclophilin D (cypD) modulates the properties of the permeability transition pore, a phenomenon implicated in the manifestation of many diseases including aging. Here, we examined the effects of partial or complete deletion of cypD on i) lifespan, ii) forebrain protein expression of 18 aging markers as well as regional expression of GFAP, mGluR1, and alpha-synuclein, and iii) behaviour of aged (>24month) male and female mice. Both male and female cypD heterozygous but not KO mice exhibited increased lifespans compared to WT littermates, associated with alterations in the protein expression of some markers, albeit without exhibiting changes in behaviour."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.org/dc/terms/identifier"doi:10.1016/j.mito.2017.03.003"xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Chinopoulos C."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Adam-Vizi V."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Pinter O."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Bodnar I."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Zelena D."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Pour-Ghaz I."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Mansour J."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Oszwald E."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/author"Vereczki V."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/name"Mitochondrion"xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/pages"115-126"xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/title"Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice."xsd:string
http://purl.uniprot.org/citations/28288917http://purl.uniprot.org/core/volume"34"xsd:string
http://purl.uniprot.org/citations/28288917http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/28288917
http://purl.uniprot.org/citations/28288917http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/28288917
http://purl.uniprot.org/uniprot/#_Q99KR7-mappedCitation-28288917http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/28288917
http://purl.uniprot.org/uniprot/Q99KR7http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/28288917