Results

RDF/XMLNTriplesTurtleShow queryShare ▶
SubjectPredicateObject
http://purl.uniprot.org/citations/28332367http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28332367http://www.w3.org/2000/01/rdf-schema#comment"

Purpose

Acute kidney injury (AKI) is common in critically ill patients. Serum cystatin C has emerged as a reliable marker of AKI. We sought to assess the value of serum cystatin C for early detection and prediction of renal function recovery in patients with sepsis.

Materials and methods

Sepsis patients (113 AKI patients and 49 non-AKI patients) admitted to the intensive care unit (ICU) were included. Serum creatinine and cystatin C levels and glomerular filtration rate were measured on days 0, 1, 3, and 7.

Results

Serum cystatin C levels were significantly higher in AKI patients than in non-AKI patients at all time points. Multivariate analysis showed that only serum cystatin C levels on day 0 were associated with AKI development [odds ratio (OR)=19.30; 95% confidence interval (CI)= 2.58-144.50, p<0.001]. Linear mixed model analysis showed significant variation in cystatin C levels between the recovery and non-recovery groups over time (p=0.001). High levels of serum cystatin C at day 0 (OR=1.64; 95% CI=1.00-2.68, p=0.048) were associated with recovery of AKI.

Conclusion

Serum cystatin C level was found to be associated with the development and worsening of AKI in ICU patients with sepsis."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.org/dc/terms/identifier"doi:10.3349/ymj.2017.58.3.604"xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Chang J."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Kim Y.S."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Kim S.K."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Kim S.Y."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Park B.H."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Kim E.Y."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Park M.S."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Song J.H."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Jung J.Y."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Chung K.S."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Jung W.J."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Kang Y.A."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/author"Leem A.Y."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/name"Yonsei Med J"xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/pages"604-612"xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/title"Value of Serum Cystatin C Measurement in the Diagnosis of Sepsis-Induced Kidney Injury and Prediction of Renal Function Recovery."xsd:string
http://purl.uniprot.org/citations/28332367http://purl.uniprot.org/core/volume"58"xsd:string
http://purl.uniprot.org/citations/28332367http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/28332367
http://purl.uniprot.org/citations/28332367http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/28332367
http://purl.uniprot.org/uniprot/#_A0A0K0K1J1-mappedCitation-28332367http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/28332367
http://purl.uniprot.org/uniprot/#_E9RH26-mappedCitation-28332367http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/28332367
▶