| http://purl.uniprot.org/citations/28345647 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28345647 | http://www.w3.org/2000/01/rdf-schema#comment | "Methylation has frequently been implicated in gender determination in plants. The recent discovery of the sex determining region (SDR) of balsam poplar, Populus balsamifera, pinpointed 13 genes with differentiated X and Y copies. We tested these genes for differential methylation using whole methylome sequencing of xylem tissue of multiple individuals grown under field conditions in two common gardens. The only SDR gene to show a marked pattern of gender-specific methylation is PbRR9, a member of the two component response regulator (type-A) gene family, involved in cytokinin signalling. It is an ortholog of Arabidopsis genes ARR16 and ARR17. The strongest patterns of differential methylation (mostly male-biased) are found in the putative promoter and the first intron. The 4th intron is strongly methylated in both sexes and the 5th intron is unmethylated in both sexes. Using a statistical learning algorithm we find that it is possible accurately to assign trees to gender using genome-wide methylation patterns alone. The strongest predictor is the region coincident with PbRR9, showing that this gene stands out against all genes in the genome in having the strongest sex-specific methylation pattern. We propose the hypothesis that PbRR9 has a direct, epigenetically mediated, role in poplar sex determination."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.org/dc/terms/identifier | "doi:10.1038/srep45388"xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Douglas C."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Cronk Q."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Campbell M.M."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Mansfield S."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Brautigam K."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Champigny M."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/author | "Soolanayakanahally R."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/name | "Sci Rep"xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/pages | "45388"xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/title | "Sexual epigenetics: gender-specific methylation of a gene in the sex determining region of Populus balsamifera."xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://purl.uniprot.org/core/volume | "7"xsd:string |
| http://purl.uniprot.org/citations/28345647 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28345647 |
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