http://purl.uniprot.org/citations/28347941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28347941 | http://www.w3.org/2000/01/rdf-schema#comment | "During development, cells adopt distinct metabolic strategies to support growth, produce energy, and meet the demands of a mature tissue. Some of these metabolic states maintain a constrained program of nutrient utilization, while others providing metabolic flexibility as a means to couple developmental progression with nutrient availability. Here we discuss our understanding of metabolic programs, and how they support specific aspects of animal development. During phases of rapid proliferation a subset of metabolic programs provide the building blocks to support growth. During differentiation, metabolic programs shift to support the unique demands of each tissue. Finally, we discuss how a model system, such as Drosophila egg development, can provide a versatile platform to discover novel mechanisms controlling programmed shift in metabolism."xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.gde.2017.03.002"xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/author | "Spradling A.C."xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/author | "Sieber M.H."xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/name | "Curr Opin Genet Dev"xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/pages | "58-68"xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/title | "The role of metabolic states in development and disease."xsd:string |
http://purl.uniprot.org/citations/28347941 | http://purl.uniprot.org/core/volume | "45"xsd:string |
http://purl.uniprot.org/citations/28347941 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28347941 |
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