| http://purl.uniprot.org/citations/28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28361874 | http://www.w3.org/2000/01/rdf-schema#comment | "The signals that maintain tissue-resident innate lymphoid cells (ILC) in different microenvironments are incompletely understood. Here we show that IL-7 receptor (IL-7R) is not strictly required for the development of any ILC subset, as residual cells persist in the small intestinal lamina propria (siLP) of adult and neonatal Il7ra-/- mice. Il7ra-/- ILC2 primarily express an ST2- phenotype, but are not inflammatory ILC2. CCR6+ ILC3, which express higher Bcl-2 than other ILC3, are the most abundant subset in Il7ra-/- siLP. All ILC subsets are functionally competent in vitro, and are sufficient to provide enhanced protection to infection with C. rodentium. IL-15 equally sustains wild-type and Il7ra-/- ILC survival in vitro and compensates for IL-7R deficiency, as residual ILCs are depleted in mice lacking both molecules. Collectively, these data demonstrate that siLP ILCs are not completely IL-7R dependent, but can persist partially through IL-15 signalling."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.org/dc/terms/identifier | "doi:10.1038/ncomms14601"xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Song W."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Colonna M."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Gilfillan S."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Ulland T.K."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Robinette M.L."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/author | "Bando J.K."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/name | "Nat Commun"xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/pages | "14601"xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/title | "IL-15 sustains IL-7R-independent ILC2 and ILC3 development."xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/28361874 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28361874 |
| http://purl.uniprot.org/citations/28361874 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28361874 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQZ2-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GQZ8-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BRC2-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_P15919-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_Q1AHQ6-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_Q1AHQ7-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_P16872-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_Q8BGR0-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |
| http://purl.uniprot.org/uniprot/#_P48346-mappedCitation-28361874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28361874 |