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http://purl.uniprot.org/citations/28392507http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28392507http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28392507http://www.w3.org/2000/01/rdf-schema#comment"Cytotoxic T lymphocyte associated gene-4 (CTLA-4) is a costimulatory molecule, expressed on the surface of activated T cells that negatively regulates T cell activation. In humans, alternative splicing of the CTLA-4 gene generates two major isoforms of mRNA, and a soluble form of CTLA-4 (sCTLA-4) was detected in normal human serum. We describe alternatively spliced mRNA expressed in peripheral blood mononuclear cells obtained from a healthy dog lacking the transmembrane domain coded by exon 3 of the CTLA-4 gene. Immunoprecipitation and western blotting of dog serum revealed a band of approximately 23-kDa, which is consistent with the predicted size, based on the amino acid sequence of the canine sCTLA-4 obtained in this study."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.org/dc/terms/identifier"doi:10.1292/jvms.16-0583"xsd:string
http://purl.uniprot.org/citations/28392507http://purl.org/dc/terms/identifier"doi:10.1292/jvms.16-0583"xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Iguchi A."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Iguchi A."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Yamamoto Y."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Yamamoto Y."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Xuan X."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Xuan X."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Miyahara K."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Miyahara K."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Tagawa M."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Tagawa M."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Shimbo G."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Shimbo G."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Tomihari M."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/author"Tomihari M."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/name"J. Vet. Med. Sci."xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/name"J Vet Med Sci"xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/pages"871-875"xsd:string
http://purl.uniprot.org/citations/28392507http://purl.uniprot.org/core/pages"871-875"xsd:string