| http://purl.uniprot.org/citations/2839467 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2839467 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2839467 | http://www.w3.org/2000/01/rdf-schema#comment | "Two phenobarbital-inducible forms of cytochrome P-450, P-450(PB-1), and P-450(PB-4), were purified from the liver microsomes of phenobarbital-treated rats and identified with P-450b and P-450e, respectively. It was found, however, that the content of P-450(PB-4) in the liver microsomes of a strain of SD rat, Qdj:SD, was very low even after phenobarbital-induction. The levels of the mRNAs for P-450(PB-1) and P-450(PB-4) were separately determined using Northern blot hybridization with specific oligonucleotide probes. It was found that the level of P-450(PB-4) mRNA in the livers of phenobarbital-treated Qdj:SD rats was much lower than that of phenobarbital-treated Slc:SD rats. Slc:SD rats are widely used in Japanese laboratories. Genetic analysis using the crossbred animals between Qdj:SD and Slc:SD rats showed that the low expression of P-450(PB-4) in Qdj:SD rats is a recessive trait and is caused by a single gene mutation. However, no difference in the 5' flanking region in P-450(PB-4) gene was found between Qdj:SD rats and Slc:SD rats."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.org/dc/terms/identifier | "doi:10.1093/oxfordjournals.jbchem.a122297"xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.org/dc/terms/identifier | "doi:10.1093/oxfordjournals.jbchem.a122297"xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Handa S."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Handa S."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Hashimoto T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Hashimoto T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Kawabata S."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Kawabata S."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Matsumoto T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Matsumoto T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Nishizawa M."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Nishizawa M."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Omura T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Omura T."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Morohashi K."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/author | "Morohashi K."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/name | "J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/name | "J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/pages | "487-492"xsd:string |
| http://purl.uniprot.org/citations/2839467 | http://purl.uniprot.org/core/pages | "487-492"xsd:string |