| http://purl.uniprot.org/citations/28420814 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28420814 | http://www.w3.org/2000/01/rdf-schema#comment | "Cell adhesion molecule 1 (CADM1) is a cell adhesion molecule that is expressed in brain, liver, lung, testis, and some kinds of cancer cells including adult T-cell leukemia/lymphoma (ATLL). Recent studies have indicated the involvement of CADM1 in cell-cell contact between cytotoxic T-lymphocytes and virus infected cells. We previously reported that cell-cell interaction between lymphoma cells and macrophages induces lymphoma cell proliferation. In the present study, we investigated whether CADM1 is associated with cell-cell interaction between several human lymphoma cell lines and macrophages.CADM1 expression was observed in the ATLL cell lines, ATN-1, ATL-T, and ATL-35T, and in the B cell lymphoma cell lines, TL-1, DAUDI, and SLVL, using western blotting. Significant cell-cell interaction between macrophages and ATN-1, ATL-T, ATL-35T and MT-2, DAUDI, and SLVL cells, as assessed by induction of cell proliferation, was observed. Immunohistochemical analysis of human biopsy samples indicated CADM1 expression in 10 of 14 ATLL cases; however, no case of follicular lymphoma or diffuse large B-cell lymphoma was positive for CADM1. Finally, the interaction of macrophages with cells of the CADM1-negative ED ATLL cell line and CADM1-transfected ED cells was tested. However, significant cell-cell interaction between macrophage and CADM1-transfected ED cells was not observed. We conclude that CADM1 was not associated with cell-cell interaction between lymphoma cells and macrophages, although CADM1 may be a useful marker of ATLL for diagnostic procedures."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.org/dc/terms/identifier | "doi:10.3960/jslrt.17003"xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Fujiwara Y."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Ma C."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Pan C."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Ohnishi K."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Saito Y."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Takeya M."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Okuno Y."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Matsuoka M."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Nosaka K."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Yano H."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Morishita K."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Komohara Y."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Wakayama T."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Shimosaki S."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/author | "Horlad H."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/name | "J Clin Exp Hematop"xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/pages | "15-20"xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/title | "Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages."xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://purl.uniprot.org/core/volume | "57"xsd:string |
| http://purl.uniprot.org/citations/28420814 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28420814 |
| http://purl.uniprot.org/citations/28420814 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28420814 |