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| http://purl.uniprot.org/citations/2846287 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila gap gene hunchback (hb) is required for the establishment of the anterior segment pattern of the embryo, and also for a small region of the posterior segment pattern. The hb gene encodes two transcripts from two promoters which show a differential regulation, although they code for the same protein product. The 3.2-kb transcript is expressed during oogenesis and forms an anterior-posterior gradient during the early stages of development. The first zygotic expression of hb during cleavage stages 11-12 is due to the 2.9-kb transcript. Its expression is under the control of the anterior pattern organizer gene bicoid (bcd) and it appears to be necessary and sufficient for the anterior segmentation. The 3.2-kb transcript is expressed again at syncytial blastoderm stage in the anterior yolk nuclei, as well as in an anterior stripe which is posteriorly adjacent to the domain of the 2.9-kb transcript, and as a posterior stripe. Using hb-promoter/lacZ fusion gene constructs in combination with germ line transformation, we have delimited a regulatory region for the 2.9-kb transcript to approximately 300 bp upstream of the site of transcription initiation and show that this region is sufficient to confer the full regulation by bcd."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.org/dc/terms/identifier | "doi:10.1002/j.1460-2075.1988.tb03145.x"xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/author | "Schroder C."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/author | "Jackle H."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/author | "Tautz D."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/author | "Seifert E."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/date | "1988"xsd:gYear |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/pages | "2881-2887"xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/title | "Differential regulation of the two transcripts from the Drosophila gap segmentation gene hunchback."xsd:string |
| http://purl.uniprot.org/citations/2846287 | http://purl.uniprot.org/core/volume | "7"xsd:string |
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