| http://purl.uniprot.org/citations/28496132 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28496132 | http://www.w3.org/2000/01/rdf-schema#comment | "Serum from one hundred and ten breast cancer patients and thirty healthy female volunteers, were prospectively collected and evaluated for serum levels of Shh and IL-6 using human Shh and IL-6 specific enzyme-linked immunoassays. All patients were regularly monitored for event free survival (EFS) and overall survival (OS). Overall outcome analysis was based on serum Shh and IL-6 levels. In patients with progressive metastatic BC, both serum Shh and IL-6 concentrations were elevated in 44% (29 of 65) and 63% (41 of 65) of patients, respectively, at a statistically significant level [Shh (p = 0.0001) and IL-6 (p = 0.0001)] compared to the low levels in healthy volunteers. Serum levels tended to increase with metastatic progression and lymph node positivity. High serum Shh and IL-6 levels were associated with poor EFS and OS opposite to the negative or lower levels in serum Shh and IL-6. The elevated levels of both serum Shh and IL-6 were mainly observed in BC patients who had a significantly higher risk of early recurrence and bone metastasis, and associated with a worse survival for patients with progressive metastatic BC. Further studies are warranted for validating these biomarkers as prognostic tools in a larger patient cohort and in a longer follow-up study."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.org/dc/terms/identifier | "doi:10.1038/s41598-017-01268-4"xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Sultana A."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Rahman S.M."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Baidya S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Alam S.S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Ara T."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Azad A.K."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Yeger H."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Aboussekhra A."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Uddin M."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Karakas B."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Jahan N."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Rashid M.I."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Rahman M.Z."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Sabri S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Ferdous J."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Akther S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Barua D."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Islam S.M.S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Islam S.S."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Siddiqua A."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Murugan A.K."xsd:string |
| http://purl.uniprot.org/citations/28496132 | http://purl.uniprot.org/core/author | "Noman A.S."xsd:string |