| http://purl.uniprot.org/citations/28698355 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28698355 | http://www.w3.org/2000/01/rdf-schema#comment | "The endocycle represents a modified mitotic cell cycle that in plants is often coupled to cell enlargement and differentiation. Endocycle onset is controlled by activity of the Anaphase Promoting Complex/Cyclosome (APC/C), a multisubunit E3 ubiquitin ligase targeting cell-cycle factors for destruction. CELL CYCLE SWITCH52 (CCS52) proteins represent rate-limiting activator subunits of the APC/C. In Arabidopsis (Arabidopsis thaliana), mutations in either CCS52A1 or CCS52A2 activators result in a delayed endocycle onset, whereas their overexpression triggers increased DNA ploidy levels. Here, the relative contribution of the APC/CCCS52A1 and APC/CCCS52A2 complexes to different developmental processes was studied through analysis of their negative regulators, being the ULTRAVIOLET-B-INSENSITIVE4 protein and the DP-E2F-Like1 transcriptional repressor, respectively. Our data illustrate cooperative activity of the APC/CCCS52A1 and APC/CCCS52A2 complexes during root and trichome development, but functional interdependency during leaf development. Furthermore, we found APC/CCCS52A1 activity to control CCS52A2 expression. We conclude that interdependency of CCS52A-controlled APC/C activity is controlled in a tissue-specific manner."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.org/dc/terms/identifier | "doi:10.1104/pp.17.00785"xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/author | "De Veylder L."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/author | "Heyman J."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/author | "Eekhout T."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/author | "Polyn S."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/name | "Plant Physiol"xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/pages | "303-313"xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/title | "Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1."xsd:string |
| http://purl.uniprot.org/citations/28698355 | http://purl.uniprot.org/core/volume | "175"xsd:string |
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