RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/28741704http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28741704http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/28741704http://www.w3.org/2000/01/rdf-schema#comment"Protein phosphatase 2A catalytic subunit (PP2A-C) has a terminal leucine subjected to methylation, a regulatory mechanism conserved from yeast to mammals and plants. Two enzymes, LCMT1 and PME1, methylate and demethylate PP2A-C, respectively. The physiological importance of these posttranslational modifications is still enigmatic. We investigated these processes in Arabidopsis thaliana by mutant phenotyping, by global expression analysis, and by monitoring methylation status of PP2A-C under different environmental conditions. The lcmt1 mutant, possessing essentially only unmethylated PP2A-C, had less dense rosettes, and earlier flowering than wild type (WT). The pme1 mutant, with 30% reduction in unmethylated PP2A-C, was phenotypically comparable with WT. Approximately 200 overlapping genes were twofold upregulated, and 200 overlapping genes were twofold downregulated in both lcmt1 and pme1 relative to WT. Differences between the 2 mutants were also striking; 97 genes were twofold upregulated in pme1 compared with lcmt1, indicating that PME1 acts as a negative regulator for these genes. Analysis of enriched GO terms revealed categories of both abiotic and biotic stress genes. Furthermore, methylation status of PP2A-C was influenced by environmental stress, especially by hypoxia and salt stress, which led to increased levels of unmethylated PP2A-C, and highlights the importance of PP2A-C methylation/demethylation in environmental responses."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.org/dc/terms/identifier"doi:10.1111/pce.13038"xsd:string
http://purl.uniprot.org/citations/28741704http://purl.org/dc/terms/identifier"doi:10.1111/pce.13038"xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Heidari B."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Heidari B."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Lillo C."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Lillo C."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Maple-Groedem J."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Maple-Groedem J."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Averkina I.O."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Averkina I.O."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Creighton M.T."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Creighton M.T."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Kataya A.R.A."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Kataya A.R.A."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Kolton A."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/author"Kolton A."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/date"2017"xsd:gYear
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/name"Plant Cell Environ."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/name"Plant Cell Environ."xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/pages"2347-2358"xsd:string
http://purl.uniprot.org/citations/28741704http://purl.uniprot.org/core/pages"2347-2358"xsd:string