| http://purl.uniprot.org/citations/2875941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2875941 | http://www.w3.org/2000/01/rdf-schema#comment | "Comparison of the nucleotide sequences of the C.C58 M75 myeloma kappa chain gene and the BALB/c germ-line J kappa segments suggested that the J kappa regions of C.C58 and BALB/c might be distinguished by restriction enzyme polymorphisms. This was shown to be the case in Southern hybridizations of Hinf I and Acc I digests of liver DNA from these and other strains with a J kappa-specific probe. Tests of a wide variety of inbred, congenic, recombinant, and recombinant-inbred strains provided evidence for three alleles, Igk-Ja, Igk-Jb, and Igk-Jc, the type strains for which are C58/J, BALB/c, and SJL/J, respectively. Analysis of the B6.PL(85NS) congenic strain suggests that the Igk-J locus lies in the neighborhood of the Lyt-2/Lyt-3 loci, approximately 0.30 cM from the V gene segment determining the Igk-VSer and Igk-Efl polymorphisms. Finally, nucleotide substitutions lead to amino acid sequence differences between the C.C58 M 75 kappa gene and the BALB/c germ line in J kappa 2 and J kappa 4. Two of these substitutions reflect true germ-line differences, raising the possibility that idiotype differences observed among strains could reflect J kappa as well as V kappa differences."xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00364742"xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/author | "Gottlieb P.D."xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/author | "Boyd R.T."xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/author | "Goldrick M.M."xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/date | "1986"xsd:gYear |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/name | "Immunogenetics"xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/pages | "150-157"xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/title | "Genetic polymorphism at the mouse immunoglobulin J kappa locus (Igk-J) as demonstrated by Southern hybridization and nucleotide sequence analysis."xsd:string |
| http://purl.uniprot.org/citations/2875941 | http://purl.uniprot.org/core/volume | "24"xsd:string |
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