| http://purl.uniprot.org/citations/28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28813670 | http://www.w3.org/2000/01/rdf-schema#comment | "The transcription factor NKX2-1 is best known for its role in the specification of subsets of cortical, striatal, and pallidal neurons. We demonstrate through genetic fate mapping and intersectional focal septal deletion that NKX2-1 is selectively required in the embryonic septal neuroepithelium for the development of cholinergic septohippocampal projection neurons and large subsets of basal forebrain cholinergic neurons. In the absence of NKX2-1, these neurons fail to develop, causing alterations in hippocampal theta rhythms and severe deficiencies in learning and memory. Our results demonstrate that learning and memory are dependent on NKX2-1 function in the embryonic septum and suggest that cognitive deficiencies that are sometimes associated with pathogenic mutations in NKX2-1 in humans may be a direct consequence of loss of NKX2-1 function."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.celrep.2017.07.053"xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Barry C."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Hausser M."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Kessaris N."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Magno L."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Schmidt-Hieber C."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/author | "Theodotou P."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/name | "Cell Rep"xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/pages | "1572-1584"xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/title | "NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory."xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/28813670 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28813670 |
| http://purl.uniprot.org/citations/28813670 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28813670 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J0A6-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_A0A0N4SWH1-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_A0A140LHC9-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_D4Q8H8-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_D4Q8I4-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_E0CZ09-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_P63015-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_A0A0N4SUJ5-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |
| http://purl.uniprot.org/uniprot/#_A0A2I3BPD4-mappedCitation-28813670 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28813670 |