http://purl.uniprot.org/citations/28904129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/28904129 | http://www.w3.org/2000/01/rdf-schema#comment | "The control of lymphoid homeostasis is the result of a very fine balance between lymphocyte production, proliferation, and apoptosis. In this study, we focused on the role of T cells in the maintenance/survival of the mature naive peripheral B cell population. We show that naive B and T cells interact via the signaling lymphocyte activation molecule (SLAM) family receptor, SLAMF6. This interaction induces cell type-specific signals in both cell types, mediated by the SLAM-associated protein (SAP) family of adaptors. This signaling results in an upregulation of the expression of the cytokine migration inhibitory factor in the T cells and augmented expression of its receptor CD74 on the B cell counterparts, consequently enhancing B cell survival. Furthermore, in X-linked lymphoproliferative disease patients, SAP deficiency reduces CD74 expression, resulting in the perturbation of B cell maintenance from the naive stage. Thus, naive T cells regulate B cell survival in a SLAMF6- and SAP-dependent manner."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1700557"xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Cohen S."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Porat Z."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Shachar I."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Stepensky P."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Bakos E."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Becker-Herman S."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Kramer M.P."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Radomir L."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Bucala R."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Barak A."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/author | "Lewinsky H."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/pages | "2745-2757"xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/title | "T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell-Cell Contact Mediated through SLAMF6 and SAP."xsd:string |
http://purl.uniprot.org/citations/28904129 | http://purl.uniprot.org/core/volume | "199"xsd:string |
http://purl.uniprot.org/citations/28904129 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28904129 |
http://purl.uniprot.org/citations/28904129 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28904129 |
http://purl.uniprot.org/uniprot/#_A0A0A6YY21-mappedCitation-28904129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28904129 |
http://purl.uniprot.org/uniprot/#_A0A0R4J0K5-mappedCitation-28904129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28904129 |
http://purl.uniprot.org/uniprot/#_E9Q9E8-mappedCitation-28904129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28904129 |
http://purl.uniprot.org/uniprot/#_A0A0R4J1S4-mappedCitation-28904129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/28904129 |