| http://purl.uniprot.org/citations/28949413 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/28949413 | http://www.w3.org/2000/01/rdf-schema#comment | "The Spinal Muscular Atrophy disease protein Survival Motor Neuron (SMN) operates as part of a multiprotein complex whose components also include Gemins 2-8 and Unrip. The fruit fly Drosophila melanogaster is thought to have a slightly smaller SMN complex comprised of SMN, Gemin2/3/5 and, possibly, Unrip. Based upon in vivo interaction methods, we have identified novel interacting partners of the Drosophila SMN complex with homologies to Gemin4/6/7/8. The Gemin4 and Gemin8 orthologues are required for neuromuscular function and survival. The Gemin6/7/Unrip module can be recruited via the SMN-associated Gemin8, hence mirroring the human SMN complex architecture. Our findings lead us to propose that an elaborate SMN complex that is typical in metazoans is also present in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.org/dc/terms/identifier | "doi:10.1002/1873-3468.12853"xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Bordonne R."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Juge F."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Cauchi R.J."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Vassallo N."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Borg R.M."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Cacciottolo R."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/author | "Lanfranco M."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/date | "2017"xsd:gYear |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/pages | "3600-3614"xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/title | "Novel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation."xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://purl.uniprot.org/core/volume | "591"xsd:string |
| http://purl.uniprot.org/citations/28949413 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/28949413 |
| http://purl.uniprot.org/citations/28949413 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/28949413 |
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