| http://purl.uniprot.org/citations/29038925 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/29038925 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectivesTo investigate whether miR-1260b can regulate migration and invasion of hepatocellular carcinoma (HCC) by targeting RGS22.ResultsmiR-1260b was up-regulated in HCC tissues compared with their corresponding non-cancerous tissues. Over-expression of miR-1260b increased migration and invasion of HepG2 and SMMC-7721 cells associated with HCC. Regulator of G-protein signaling 22 (RGS22) was identified as a directly target of miR-1260b and was inhibited by miR-1260b. Knockdown of RGS22 increased proliferation of HCC cells.ConclusionsThe new identified miR-1260b/RGS22 axis provides useful therapeutic methods for treatment of HCC deepening on our understanding of underlying mechanisms of HCC tumorigenesis."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10529-017-2455-6"xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/author | "Bi Y."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/author | "Song H."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/name | "Biotechnol Lett"xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/pages | "57-62"xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/title | "miR-1260b promotes cell migration and invasion of hepatocellular carcinoma by targeting the regulator of G-protein signaling 22."xsd:string |
| http://purl.uniprot.org/citations/29038925 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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