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http://purl.uniprot.org/citations/29052270http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29052270http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/29052270http://www.w3.org/2000/01/rdf-schema#comment"The dual specificity phosphatase DUSP1 was the first mitogen activated protein kinase phosphatase (MKP) to be identified. It dephosphorylates conserved tyrosine and threonine residues in the activation loops of mitogen activated protein kinases ERK2, JNK1 and p38-alpha. Here, we report the crystal structure of the human DUSP1 catalytic domain at 2.49 Å resolution. Uniquely, the protein was crystallized as an MBP fusion protein in complex with a monobody that binds to MBP. Sulfate ions occupy the phosphotyrosine and putative phosphothreonine binding sites in the DUSP1 catalytic domain."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.org/dc/terms/identifier"doi:10.1002/pro.3328"xsd:string
http://purl.uniprot.org/citations/29052270http://purl.org/dc/terms/identifier"doi:10.1002/pro.3328"xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Waugh D.S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Waugh D.S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Tropea J.E."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Tropea J.E."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Cherry S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Cherry S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Lountos G.T."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Lountos G.T."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Gumpena R."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Gumpena R."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Raran-Kurussi S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/author"Raran-Kurussi S."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/date"2018"xsd:gYear
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/name"Protein Sci."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/name"Protein Sci."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/pages"561-567"xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/pages"561-567"xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/title"Crystal structure of the human dual specificity phosphatase 1 catalytic domain."xsd:string
http://purl.uniprot.org/citations/29052270http://purl.uniprot.org/core/title"Crystal structure of the human dual specificity phosphatase 1 catalytic domain."xsd:string