http://purl.uniprot.org/citations/29161980 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/29161980 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundThe aim of the study is to determine the prognostic relevance of CD200/ CD56 expression in adult acute lymphoblastic leukemia patients.MethodsThe expression of CD200 and CD56 by blast cells was assessed by flow cytometry before the start of chemotherapy in 70 B-ALL patients.ResultsPositive expression of CD200 was detected in forty-six patients (66%) and CD56 was detected in 7 patients (10%) out of 70 patients, respectively. Only three patients (4.3%) had co-expression for CD200+ and CD56+. Splenomegaly and thrombocytopenia were frequently observed more in CD200+ patients. Increased frequency of CD34+ was associated with CD200+and CD56+ patients. The CD200+ and CD56+ subgroups of B-ALL patients had inferior OS and disease free survival compared to CD 200- and CD 56- patients.ConclusionsCD200+ and/or CD56+ positive expression in B-ALL patients at diagnosis is a poor prognostic biomarker. Identification of CD200+ and CD56+ expression at diagnosis is recommended for a better stratification of adult B-ALL patients."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.org/dc/terms/identifier | "doi:10.1080/10245332.2017.1404276"xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/author | "Ibrahim L."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/author | "Aref S."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/author | "Mabed M."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/author | "Azmy E."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/author | "El-Bakry K."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/date | "2018"xsd:gYear |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/name | "Hematology"xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/pages | "263-270"xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/title | "Prognostic impact of CD200 and CD56 expression in adult acute lymphoblastic leukemia patients."xsd:string |
http://purl.uniprot.org/citations/29161980 | http://purl.uniprot.org/core/volume | "23"xsd:string |
http://purl.uniprot.org/citations/29161980 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/29161980 |
http://purl.uniprot.org/citations/29161980 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/29161980 |
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http://purl.uniprot.org/uniprot/P13591 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/29161980 |
http://purl.uniprot.org/uniprot/A0A087WWD4 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/29161980 |
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